For openers, it depends what you are playing as/against. Like you said it is all very situational, but here are some general tips:
My preferred opener if you want to get pressure out quickly would be garrote > ss spam > 5cp snd > mfd+clone+kidney > killing spree > ar.
If you are playing as/against double dps in 2s then garrote > clone+killing spree works for tons of unavoidable damage in some cases
For ret rog priest I like garrote > revealing strike > mfd kidney for a strong opener on healers. Coordinate interrupts from there and save clone until they trinket.
jojobombiestMember Since 11 Feb 2008
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